Sub-Tenon or subconjunctival administration of carboplatin is used to consolidate tumor
regression by achieving high intraocular concentrations, without incurring systemic toxicity,
in selected patients with intraocular retinoblastoma. Mild transient periocular edema is a
common side effect of this treatment. We describe four patients with severe local soft-tissue
toxic reaction mimicking preseptal cellulitis following subtenon carboplatin injections. The
development of this complication after injecting through the inferior conjunctiva and …