New paradigms and future challenges in radiation oncology: an update of biological targets and technology

SL Liauw, PP Connell, RR Weichselbaum - Science translational …, 2013 - science.org
Science translational medicine, 2013science.org
Radiation oncology exploits the biological interaction of radiation within tissue to promote
tumor death while minimizing damage to surrounding normal tissue. The clinical delivery of
radiation relies on principles of radiation physics that define how radiation energy is
deposited in the body, as well as technology that facilitates accurate tumor targeting. This
review will summarize the current landscape of recent biological and technological
advances in radiation oncology, describe the challenges that exist, and offer potential …
Radiation oncology exploits the biological interaction of radiation within tissue to promote tumor death while minimizing damage to surrounding normal tissue. The clinical delivery of radiation relies on principles of radiation physics that define how radiation energy is deposited in the body, as well as technology that facilitates accurate tumor targeting. This review will summarize the current landscape of recent biological and technological advances in radiation oncology, describe the challenges that exist, and offer potential avenues for improvement.
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