Orexin A excites serotonergic neurons in the dorsal raphe nucleus of the rat
Orexin A (10–300 nM) strongly excited dorsal raphe serotonergic neurons maintained in
vitro. The depolarization persisted in the presence of tetrodotoxin (TTX, 0.5 μM) and was
associated with an increase in input resistance. These results have relevance in the context
of food intake regulation and the disease, narcolepsy.
vitro. The depolarization persisted in the presence of tetrodotoxin (TTX, 0.5 μM) and was
associated with an increase in input resistance. These results have relevance in the context
of food intake regulation and the disease, narcolepsy.
Orexin A (10–300 nM) strongly excited dorsal raphe serotonergic neurons maintained in vitro. The depolarization persisted in the presence of tetrodotoxin (TTX, 0.5 μM) and was associated with an increase in input resistance. These results have relevance in the context of food intake regulation and the disease, narcolepsy.
Elsevier
