Persistent changes in ability to express long-term potentiation/depression in the rat hippocampus after juvenile/adult stress
N Maggio, M Segal - Biological psychiatry, 2011 - Elsevier
BACKGROUND: The ventral hippocampus (VH) was recently shown to express lower
magnitude long-term potentiation (LTP) compared with the dorsal hippocampus (DH).
Exposure to acute stress reversed this difference, and VH slices from stressed rats
expressed larger LTP than that produced in the DH, which was reduced by stress. Stressful
experience in adolescence has been shown to produce long-lasting effects on animal
behavior and on ability to express LTP/long-term depression (LTD) of reactivity to afferent …
magnitude long-term potentiation (LTP) compared with the dorsal hippocampus (DH).
Exposure to acute stress reversed this difference, and VH slices from stressed rats
expressed larger LTP than that produced in the DH, which was reduced by stress. Stressful
experience in adolescence has been shown to produce long-lasting effects on animal
behavior and on ability to express LTP/long-term depression (LTD) of reactivity to afferent …
