The mouse inoculation test in rabies diagnosis: early diagnosis in mice during the incubation period.
WA Webster, GA Casey, KM Charlton - Canadian Journal of …, 1976 - ncbi.nlm.nih.gov
WA Webster, GA Casey, KM Charlton
Canadian Journal of Comparative Medicine, 1976•ncbi.nlm.nih.govBrain tissue from 64 rabies suspect specimens were inoculated intracerebrally into twenty 9-
12 gm adult Swiss white mice. Two mice from each specimen were killed on specific days
postinoculation and examined for the presence of rabies virus by the fluorescent antibody
staining technique. In this way a positive diagnosis was made in the majority of cases
between postinoculation days 4 and 12 when the incubation period of these same
specimens ranged between eight and 20 days.
12 gm adult Swiss white mice. Two mice from each specimen were killed on specific days
postinoculation and examined for the presence of rabies virus by the fluorescent antibody
staining technique. In this way a positive diagnosis was made in the majority of cases
between postinoculation days 4 and 12 when the incubation period of these same
specimens ranged between eight and 20 days.
Abstract
Brain tissue from 64 rabies suspect specimens were inoculated intracerebrally into twenty 9-12 gm adult Swiss white mice. Two mice from each specimen were killed on specific days postinoculation and examined for the presence of rabies virus by the fluorescent antibody staining technique. In this way a positive diagnosis was made in the majority of cases between postinoculation days 4 and 12 when the incubation period of these same specimens ranged between eight and 20 days.
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