Hypoxia: the force that drives chronic kidney disease

Q Fu, SP Colgan, CS Shelley - Clinical medicine & research, 2016 - Marshfield Clinic
In the United States the prevalence of end-stage renal disease (ESRD) reached epidemic
proportions in 2012 with over 600,000 patients being treated. The rates of ESRD among the
elderly are disproportionally high. Consequently, as life expectancy increases and the baby-
boom generation reaches retirement age, the already heavy burden imposed by ESRD on
the US health care system is set to increase dramatically. ESRD represents the terminal
stage of chronic kidney disease (CKD). A large body of evidence indicating that CKD is …