[HTML][HTML] Reduction of HIV persistence following transplantation in HIV-infected kidney transplant recipients
PG Stock, B Barin, H Hatano, RL Rogers… - American journal of …, 2014 - Elsevier
Chronic inflammation may contribute to human immunodeficiency virus (HIV) persistence
through a number of potential pathways. We explored the impact of immunosuppressant
therapy on peripheral blood measures of HIV persistence following kidney transplantation.
Stored plasma and peripheral blood mononuclear cells prior to transplantation and at weeks
12, 26, 52 and 104 posttransplant were obtained from 91 transplant recipients. In a
multivariate model, higher pretransplant plasma HIV RNA level (p< 0.0001) and a longer …
through a number of potential pathways. We explored the impact of immunosuppressant
therapy on peripheral blood measures of HIV persistence following kidney transplantation.
Stored plasma and peripheral blood mononuclear cells prior to transplantation and at weeks
12, 26, 52 and 104 posttransplant were obtained from 91 transplant recipients. In a
multivariate model, higher pretransplant plasma HIV RNA level (p< 0.0001) and a longer …