[HTML][HTML] Sensitization of primary afferent nociceptors induced by intradermal capsaicin involves the peripheral release of calcitonin gene-related Peptide driven by …
D Li, Y Ren, X Xu, X Zou, L Fang, Q Lin - The Journal of Pain, 2008 - Elsevier
Neuropeptides released from axons of primary afferent nociceptive neurons are the key
elements for the incidence of neurogenic inflammation and their release is associated with
dorsal root reflexes (DRRs). However, whether the release is due to the triggering of DRRs
and plays a role in inflammation-induced pain still remain to be determined. The present
study assessed the role of calcitonin gene-related peptide (CGRP) in sensitization of primary
afferent nociceptors induced by activation of transient receptor potential vanilloid-1 (TRPV1) …
elements for the incidence of neurogenic inflammation and their release is associated with
dorsal root reflexes (DRRs). However, whether the release is due to the triggering of DRRs
and plays a role in inflammation-induced pain still remain to be determined. The present
study assessed the role of calcitonin gene-related peptide (CGRP) in sensitization of primary
afferent nociceptors induced by activation of transient receptor potential vanilloid-1 (TRPV1) …
