Repeated measures

LM Sullivan - Circulation, 2008 - Am Heart Assoc
Circulation, 2008Am Heart Assoc
quintiles of age) with 1 replication per group (k 4, b 5, r 1). In a randomized block design,
experimental units within each block are randomly assigned to treatments, and this
technique reduces variation due to differences in age. The design can be thought of as
replications of a completely randomized experiment in which there are as many replications
as there are blocks. Some repeated-measures designs can be viewed as a special case of
the randomized block design in which the block is the individual experimental unit (eg …
quintiles of age) with 1 replication per group (k 4, b 5, r 1). In a randomized block design, experimental units within each block are randomly assigned to treatments, and this technique reduces variation due to differences in age. The design can be thought of as replications of a completely randomized experiment in which there are as many replications as there are blocks.
Some repeated-measures designs can be viewed as a special case of the randomized block design in which the block is the individual experimental unit (eg, person or animal). The randomized block design is often used with siblings or littermates. The family unit is the block, and assessments are repeated on each member of the family. The assessments within a family or litter are related. Accounting for the dependencies within the block results in a more precise test of treatment differences.
Am Heart Assoc