Context Sleep-disordered breathing (characterized by recurrent arousals from sleep and
intermittent hypoxemia) is common among older adults. Cross-sectional studies have linked
sleep-disordered breathing to poor cognition; however, it remains unclear whether sleep-
disordered breathing precedes cognitive impairment in older adults. Objectives To
determine the prospective relationship between sleep-disordered breathing and cognitive
impairment and to investigate potential mechanisms of this association. Design, Setting, and …